GMP manufacturing capability supports any preclinical, clinical, and commercial scale manufacturing of a wide range of viral vector platforms – Lenti, Adeno, Retro, and Baculo.
Driven by scale flexibility, we can support on a wide scale of operation – 0.5L – 1,000L. Utilization of single-use technologies enable prompt change over by omitting cleaning validation.
We undertake an integrated approach to safety and quality management systems, which enable greater flexibility by leveraging pan – organizational experience in managing regulatory audits, and compliance to statutory norms.
Plasmid production and characterization
Lentivirus: Gag-pol, VSVG, Rev, and Transfer plasmids (3rd Gen system)
Recombinant adeno-associated virus (rAAV): Packaging plasmid (Rep-Cap), helper plasmid (VA-E2A-E4), and transfer plasmids
- GMP like
- Digestion and sequencing
Upstream process development
- HEK293T suspension / adherent
- Transfection (PEI or other methods)
- Shake flask, wave bioreactors, stirred-tank reactor, and iCELLis
Purification
Purification is done using ultracentrifuge or chromatography
- Clarification and concentration, TFF, and Benzonase
- Ultracentrifuge or chromatography (IEX, AEX, affinity, and SEC)
- Concentration and buffer exchange, TFF, and sterile filtration
QC and release
Release assay
- General/physical properties
- Identity
- Safety
- Purity
- Strength
- Potency
Viral Vaccine
Our viral vaccine manufacturing facility can cater to both – conventional and novel viral vaccines.
Our manufacturing capability (GMP/ Non-GMP) supports preclinical, clinical, and commercial scale manufacturing of a wide range of viral vaccines in suspension or combination of adherent and suspension methods.
We can support large- scale vaccine manufacturing – 2x1KL per batch run in a single-use platform. Manufacturing is supported by an in-house capability of viral vaccine development and MSAT.
Why Aurigene Viral Vectors Services?
2KL installed capacity
Low lead time to manufacturing.
30+ tech operation professionals
Zero liquid discharge capability
Integrated approach to safety and quality management systems
One-stop shop across the product life cycle – proof of concept to commercial
Integrated QC testing and release
Virtual Tour
Hyderabad R and D Center
Bangalore R and D Center
Connect with our scientific experts for your drug discovery, development, and manufacturing needs
We understand that clear communication is essential to successful collaborations, and that's why we have a dedicated team that is always ready to help you. Whether you have questions about our services, want to discuss a potential partnership, or simply want to learn more about our company, we're here to help.
Our team of experts is dedicated to providing personalised solutions tailored to your unique needs. So, please don't hesitate to reach out to us. We look forward to hearing from you and helping you achieve your business goals.
Methoxy Polyethylene Glycol (m-PEGs)
Aurigene Pharmaceutical Services is a leader in the synthesis of activated MethoxyPolyethyleneGlycol(m-PEGs), With a comprehensive product range and customized services. ...
Read More
Base mediated spirocyclization of quinazoline: one-step synthesis of spiro-isoindolinone dihydroquinazolinones
2020
A novel approach for the spiro-isoindolinone dihydroquinazolinones has been demonstrated from 2- aminobenzamide and 2-cyanomethyl benzoate in the presence of KHMDS as a base to get moderate yields. The reaction has been screened in various bases followed by solvents and a gram scale reaction has also been executed under the given conditions. Based on the controll...
Read More-
Ultrasound assisted rapid synthesis of mefenamic acid based indole derivatives under ligand free Cu-catalysis: Their pharmacological evaluation
2005
An improved and rapid synthesis of mefenamic acid based indole derivatives has been achieved via the ligand free Cu-catalyzed coupling-cyclization method under ultrasound irradiation. This simple, straightforward and inexpensive one-pot method involved the reaction of a terminal alkyne derived from mefenamic acid with 2- iodosulfanilides in the presence of CuI ...
Read More -
Formal synthesis of Cladospolide C & epi-Cladospolide C using R- (þ)-g-valerolactone as a chiral synthon
2005
The formal synthesis of Cladospolide-C and its analog is achieved by using enantiopure (R)-g evalerolactone 10. The significant points of this synthesis are the stereoselective dihydroxylation of a, bunsaturated ester 16 using Sharpless protocol, Wittig olefination of g evalerolactol 6 with triphenylphosphonium iodide salt 7, one pot selective oxidation ...
Read More -
Amberlite-15 promoted an unprecedented aza Michael rearrangement for one pot synthesis of dihydroquinazolinone compounds
2005
A new one pot multicomponent annulation strategy for the synthesis of various dihydroquinazolinone compounds has been developed using Amberlite-15 as a catalyst, giving good to moderate yields. In this reaction the substrate scope for amines and aldehydes was also investigated. The reaction has been checked on a large scale ...
Read More
You are about to leave Aurigene Pharmaceutical Services and affiliates website. Aurigene Pharmaceutical Services assumes no responsibility for the information presented on the external website or any further links from such sites. These links are presented to you only as a convenience, and the inclusion of any link does not imply endorsement by Aurigene Pharmaceutical Services.
If you wish to continue to this external website, click Proceed.
Leaving already?
Don't forget to join us at
CPHI Worldwide 2023.
October 24th-26th, 2023 | Barcelona, Spain
Get ready to accelerate your drug’s journey to the market