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Development and Manufacturing
Emerging Trends in Solid Phase Peptide Synthesis
FEBRUARY 23, 2021
Development and Manufacturing
Application & Manufacturing of High Potent Active Pharmaceutical Ingredient (HPAPI)
JANUARY 04, 2021
Development and Manufacturing
Application of mPEGs in Drug Discovery and Development
JANUARY 04, 2021
Discovery, Development and Manufacturing Services
High Potent API (HPAPI) Manufacturing Services
Formulation Development Services
Custom Peptide Synthesis
Accelerating Drug Discovery Through Innovative Partnerships
Evolution in Pharma Industry and Demand for Integrated CDMO
Peptide Development and Manufacturing
HPAPI Molecule from Development to Market
HPAPI Development at a Glance
Ultrasound assisted rapid synthesis of mefenamic acid based indole derivatives under ligand free Cu-catalysis: Their pharmacological evaluation
Formal synthesis of Cladospolide C & epi-Cladospolide C using R- (þ)-g-valerolactone as a chiral synthon
Amberlite-15 promoted an unprecedented aza Michael rearrangement for one pot synthesis of dihydroquinazolinone compounds
A convergent approach towards the synthesis of the 2-alkylsubstituted tetrahydroquinoline alkaloid ()-cuspareine
A diastereoselective synthesis of boceprevir's gem-dimethyl bicyclic [3.1.0] proline intermediate from an insecticide ingredient ciscypermethric acid
Synthesis of (+)-Patulolide C Using R-(+)-g-Valerolactone as a Chiral Synthon.
Synthesis of 2-hydroxy-3-alkyl-2-phenyl-2,3- dihydroquinazolin-4(1H)-one via molybdenum hexacarbonyl mediated CO gas- and ligand free carbonylative reactions
Stereoselective synthesis of (R)-() and (S)-(+)-phoracantholide I from (R)-(+)-c-valerolactone
An efficient and convenient protocol for the synthesis of tetracyclic isoindolo[1,2-a]quinazoline derivatives
A Simple Approach for the Synthesis of Fused Quinazoline-Based Tetracyclic Compounds via a Multicomponent Reaction Strategy
A concise stereoselective synthesis of (+)-1-deoxy-6-epicastanospermine
Development of a Chemoenzymatic Process for Dehydroepiandrosterone Acetate Synthesis
A cascade reaction for the new and direct synthesis of indolofuroquinoxalines
Concise and highly stereoselective syntheses of D-fagomine and 2-epi-fagomine
A new strategy for accessing (S)-1-(furan-2-yl)pent-4-en-1-ol: a key precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins
FeF3-catalyzed MCR in PEG-400: ultrasound assisted synthesis of N-substituted 2- aminopyridines
Diversity oriented concise asymmetric synthesis of azasugars: a facile access to L-2,3-trans-3,4-cis-dihydroxyproline and (3S,5S)-3,4,5-trihydroxypiperidine
Diastereoselective total synthesis of piperidine alkaloids: (2R,5R)- 5-hydroxyhomopipecolic acid and (2R,5R,8R)-5-hydroxysedamine
An efficient one pot synthesis of 2-amino quinazolin-4(3H)-one derivative via MCR strategy
Sulfonic acid functionalized Wang resin (Wang-OSO3H) as polymeric acidic catalyst for the eco-friendly synthesis of 2,3-dihydroquinazolin-4(1H)-ones
A short diastereoselective synthesis of cis-(2S,4S) and cis-(2R,4R)-4- hydroxyprolines
A greener approach towards double heteroarylation of N, O and S nucleophiles: synthesis of bioactive polynuclear fused Nheteroarenes
A metal catalyst-free and one-pot synthesis of (3,4- dihydro-2H-benzo[b][1,4]oxazin-2-yl)methanol derivatives in water
An oxidative amidation and heterocyclization approach for the synthesis of β-carbolines and dihydroeudistomin Y
Applications of Gage Reproducibility & Repeatability (GRR): Understanding and Quantifying the Effect of Variations from Different Sources on a Robust Process Development
A simple access to N-(un)substituted isoquinolin1(2H)-ones: unusual formation of regioisomeric isoquinolin-1(4H)-ones
Reactions of salicylaldehydes with activated terminal alkynes in aqueous media: synthesis of 3- substituted 4-hydroxy chromenes as potential cytotoxic agents
Synthesis of tetrahedral diarylheptanoid ent-diospongin A and epimer-diospongin B by employing Julia–Kocienski olefination
Synthesis of tetrahedral diarylheptanoid ent-diospongin A and epimer-diospongin B by employing Julia–Kocienski olefination
Effect of Aqueous Polyethylene Glycol on 1,3-Dipolar Cycloaddition of Benzoylnitromethane/Ethyl 2-Nitroacetate with Dipolarophiles: Green Synthesis of Isoxazoles and Isoxazolines
Diastereoselective total synthesis of 3,6-disubstituted piperidine alkaloids, (3R,6S)-epi-pseudoconhydrine and (3R,6R)-pseudoconhydrine
Synthesis of enantiomerically pure N-(2,3-dihydroxypropyl)arylamides via oxidative esterification
Cu-catalyzed coupling-cyclization in PEG 400 under ultrasound: a highly selective and greener approach towards isocoumarins
N-heterocyclic carbene-mediated hydroacylation–Sonogashira/Heck/Suzuki coupling in a single pot: A new cascade reaction
Synthesis of Isoquinoline Alkaloids via Oxidative Amidation–Bischler– Napieralski Reaction
Iodine catalyzed four-component reaction: a straightforward one-pot synthesis of functionalized pyrroles under metal-free conditions
Construction of a six-membered fused N-heterocyclic ring via a new 3-component reaction: synthesis of (pyrazolo)pyrimidines/pyridinesw
An Efficient and Practical Synthesis of Aryl and Hetaryl a-Keto Esters
Construction of a quinoline ring via a 3-component reaction in water: crystal structure analysis and H-bonding patterns of a 2-aryl quinoline
Synthesis of novel 5-alkyl/aryl/heteroaryl substituted diethyl 3,4-dihydro-2H-pyrrole-4,4-dicarboxylates by aziridine ring expansion of 2-[(aziridin-1-yl)-1-alkyl/ aryl/heteroaryl-methylene]malonic acid diethyl esters
Transition metal mediated construction of pyrrole ring on 2,3-dihydroquinolin-4(1H)-one: synthesis and pharmacological evaluation of novel tricyclic heteroarenes
Yb(OTf)3 catalyzed new cascade reaction: a facile assembly of fused quinazolinones
A Concise and Cascade Synthesis of Batracylin and Substituted Isoindolo- [1,2-b]quinazolin-12(10H)-ones
A Concise and Convergent Synthesis of Luotonin B and E
A highly effective synthesis of 2-alkynyl-7-azaindoles: Pd/C-mediated alkynylation of heteroaryl halides in water
Revisiting the reaction of b-chloroacroleins with 2-aminophenol: a new observation
Tandem versus single C–C bond forming reaction under palladium–copper catalysis: regioselective synthesis of a-pyrones fused with thiophene
Palladium-mediated synthesis of 5-substituted 4-alkynylthieno[2,3-c]pyran-7-onesq
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