At Aurigene, we provide end-to-end antibody discovery solutions that power the development of traditional monoclonal antibodies as well as advanced therapeutic formats including bispecifics (bsAbs), multispecifics, antibody-drug conjugates (ADCs), and CAR T-cell therapies. Leveraging a suite of proprietary platforms, screening tiers, fit-for-purpose tools, and scientific expertise, our services are designed to meet the diverse and evolving needs of drug developers.
Key Technologies & Proprietary Platforms
Our key technologies and proprietary platforms include:
- B-CAD: B-cell cultur platform for high-affinity, high-diversity, and high-throughput screening
- HyFusn: Hybridoma generation with high-efficiency fusion techniques
- Display Platforms: Phage and yeast display libraries, including synthetic nanobody library
- Antibody Engineering: Humanization, affinity maturation, Fc engineering, in silico developability, conjugation and Reformatting in bispecific/multispecific/CAR designs
- Comprehensive Screening Suite: Flow cytometry, ELISA, Octet, SPR, and fit-for-purpose functional assays
Workflow Overview
Our integrated discovery workflow includes:
- Antigen Design & Immunization
- Hybridoma and B-cell Platforms
- Fit-for-purpose screening & Characterization
- Antibody Engineering & Optimization
- Functional Evaluation & Candidate Selection
Why Choose Aurigene for Antibody Discovery?
State-of-the-art, AAALAC-accredited animal facilities
Proprietary high-throughput platforms for accelerated timelines
Deep expertise indiscovering high affinity antibodies
Customizable programs for diverse therapeutic endpoints
Seamless integration from immunogen design to final candidate delivery
Virtual Tour
Hyderabad R and D Center
Bangalore R and D Center
Connect with our scientific experts for your drug discovery, development, and manufacturing needs
We understand that clear communication is essential to successful collaborations, and that's why we have a dedicated team that is always ready to help you. Whether you have questions about our services, want to discuss a potential partnership, or simply want to learn more about our company, we're here to help.
Our team of experts is dedicated to providing personalised solutions tailored to your unique needs. So, please don't hesitate to reach out to us. We look forward to hearing from you and helping you achieve your business goals.
Methoxy Polyethylene Glycol (m-PEGs)
Aurigene Pharmaceutical Services is a leader in the synthesis of activated MethoxyPolyethyleneGlycol(m-PEGs), With a comprehensive product range and customized services. ...
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Base mediated spirocyclization of quinazoline: one-step synthesis of spiro-isoindolinone dihydroquinazolinones
2020
A novel approach for the spiro-isoindolinone dihydroquinazolinones has been demonstrated from 2- aminobenzamide and 2-cyanomethyl benzoate in the presence of KHMDS as a base to get moderate yields. The reaction has been screened in various bases followed by solvents and a gram scale reaction has also been executed under the given conditions. Based on the controll...
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Ultrasound assisted rapid synthesis of mefenamic acid based indole derivatives under ligand free Cu-catalysis: Their pharmacological evaluation
2005
An improved and rapid synthesis of mefenamic acid based indole derivatives has been achieved via the ligand free Cu-catalyzed coupling-cyclization method under ultrasound irradiation. This simple, straightforward and inexpensive one-pot method involved the reaction of a terminal alkyne derived from mefenamic acid with 2- iodosulfanilides in the presence of CuI ...
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Formal synthesis of Cladospolide C & epi-Cladospolide C using R- (þ)-g-valerolactone as a chiral synthon
2005
The formal synthesis of Cladospolide-C and its analog is achieved by using enantiopure (R)-g evalerolactone 10. The significant points of this synthesis are the stereoselective dihydroxylation of a, bunsaturated ester 16 using Sharpless protocol, Wittig olefination of g evalerolactol 6 with triphenylphosphonium iodide salt 7, one pot selective oxidation ...
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Amberlite-15 promoted an unprecedented aza Michael rearrangement for one pot synthesis of dihydroquinazolinone compounds
2005
A new one pot multicomponent annulation strategy for the synthesis of various dihydroquinazolinone compounds has been developed using Amberlite-15 as a catalyst, giving good to moderate yields. In this reaction the substrate scope for amines and aldehydes was also investigated. The reaction has been checked on a large scale ...
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