Our B-CAD platform and single B-cell sequencing workflows allow for rapid, high-affinity, and diverse antibody discovery directly from antigen specific memory B cells.
Key Platforms & Technologies
B-CAD B-cell Culture Platform
- Antigene specific single B cell sorting per well in 384-well plate
- B-cell culture up to 50–100 cells per well in 384-well format
- Culture media enriched with proprietary cytokines/growth factors
- Supernatant screening: ELISA, flow cytometry, Octet, SPR
- Turnaround Time (TAT): 2–3 weeks
Single B-cell Sequencing
- Direct recovery of V-genes from antigen-specific B cells
- Rapid reformatting, expression, and screening
- High diversity, improved developability
Advantages
- Faster timelines than traditional hybridoma workflows
- Greater antibody diversity and affinity range
- High developability and cost-effectiveness
- Compatible with high-throughput liquid handling
Why Choose Aurigene?
Proprietary B-cell culture platform enabling rapid antibody discovery
Antigen specific Mmemory B-cell selection for better candidates
Integrated sequencing and expression pipeline
Superior candidate quality and productivity
Virtual Tour
Hyderabad R and D Center
Bangalore R and D Center
Connect with our scientific experts for your drug discovery, development, and manufacturing needs
We understand that clear communication is essential to successful collaborations, and that's why we have a dedicated team that is always ready to help you. Whether you have questions about our services, want to discuss a potential partnership, or simply want to learn more about our company, we're here to help.
Our team of experts is dedicated to providing personalised solutions tailored to your unique needs. So, please don't hesitate to reach out to us. We look forward to hearing from you and helping you achieve your business goals.
Methoxy Polyethylene Glycol (m-PEGs)
Aurigene Pharmaceutical Services is a leader in the synthesis of activated MethoxyPolyethyleneGlycol(m-PEGs), With a comprehensive product range and customized services. ...
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A novel approach for the spiro-isoindolinone dihydroquinazolinones has been demonstrated from 2- aminobenzamide and 2-cyanomethyl benzoate in the presence of KHMDS as a base to get moderate yields. The reaction has been screened in various bases followed by solvents and a gram scale reaction has also been executed under the given conditions. Based on the controll...
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2005
An improved and rapid synthesis of mefenamic acid based indole derivatives has been achieved via the ligand free Cu-catalyzed coupling-cyclization method under ultrasound irradiation. This simple, straightforward and inexpensive one-pot method involved the reaction of a terminal alkyne derived from mefenamic acid with 2- iodosulfanilides in the presence of CuI ...
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Formal synthesis of Cladospolide C & epi-Cladospolide C using R- (þ)-g-valerolactone as a chiral synthon
2005
The formal synthesis of Cladospolide-C and its analog is achieved by using enantiopure (R)-g evalerolactone 10. The significant points of this synthesis are the stereoselective dihydroxylation of a, bunsaturated ester 16 using Sharpless protocol, Wittig olefination of g evalerolactol 6 with triphenylphosphonium iodide salt 7, one pot selective oxidation ...
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2005
A new one pot multicomponent annulation strategy for the synthesis of various dihydroquinazolinone compounds has been developed using Amberlite-15 as a catalyst, giving good to moderate yields. In this reaction the substrate scope for amines and aldehydes was also investigated. The reaction has been checked on a large scale ...
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