Oligonucleotide Synthesis Services

Oligonucleotide Synthesis Services

At our state-of-the-art drug discovery facility for oligonucleotide synthesis, our team accelerates your early drug discovery. With years of experience in small molecules, we can design molecules, overcoming bioavailability issues, and devising a fast-forward approach for your oligo targets across therapeutic areas such as oncology, inflammation, and anti-bacterial, etc.
Our dedicated oligonucleotide platform helps to encapsulate oligonucleotide molecules for better bioavailability, and CADD trained team helps optimize the designed oligonucleotide along with primary assay iterations. We can Synthesis 10-40-mer oligonucleotide up to 1 gram scale. We can perform all standard modifications, with or without backbone modification, for which phosphoramidites are commercially available. We also have the capabilities of making any customized phosphoramidite in-house

Our Oligonucleotide synthesis services is backed by:

• K&A H-16 automated DNA/RNA synthesizer
• AKTA pure 25M FPLC purification system
• Sartoflow smart TFF system for concentration and desalting
• Martin Christ LSC plus lyophilizer with lyocube, benchtop tray lyophilizer
• Agilent LCMS for oligonucleotide analysis
• Implen N60 nano spectrophotometer